Causes of amputation (leg cut off) are so many but diabetes is one of the leading causes of amputation of the lower limbs worldwide.
While the problems of the foot are the most frequent reason for hospitalisation among patients with diabetes, high blood sugar in diabetes puts stimulates certain cells which eat up the bones. The cells that eat up the bones weaken the bones making them soft and pudgy.
Foot ulcers if unattended to well can act as entry point for the bacteria that may lead one to have his or her legs cut off. Other causes of amputation are accidents and cancers.
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