Symptoms of osteomyelitis are many. They develop and stay for over a relatively some period. Acute osteomyelitis is difficult to determine because people relate it to trauma or a child falling down.

The major signs of osteomyelitis include: pain in the affected bone, tenderness to pressure and arise in temperature over the infected area.

One can also get muscle spasms in the inflamed area, fever and chills which resolve in about 3 days but recur with the swelling. Pus is also produced within the bone resulting in a foul-smelling discharge.

The thigh bone (also called the femur), the lower leg (tibia) or the bone of the upper arm (read humerus) is the most likely sites of infection. This is because in children these bones have particular high blood circulation, making them more susceptible to bacteria invasion.